The paper aims to critically resort to the materialist-geographical concept of the ‘spatial fix’ for deepening understanding of the functioning of ancient Mediterranean polytheism as urban religion. In its second and main part, it focuses on a few selected samples of the early Christian critique of the polytheist production of a religious built environment in order to better foreground the spatialized character of these polemical arguments. Lastly, it touches on the major changes occurred in this polemical discourse at the time of the increasing ‘materialization’ of Christian religious space.